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Nonetheless, caregivers of children who had all received active IPTc were considerably more likely to attribute the morbidity reductions specifically to IPTc, whereas those whose children received placebo were more likely to attribute benefits more vaguely to “the project.

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Treatment of Acute Malaria: Daraprim is also indicated for the treatment of acute malaria.

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In FGDs, caregivers and CHWs discussed a number of strategies to ensure that all children in the catchment area of each health post, including those living in more distant villages, would receive all nine doses of IPTc if the health service were to decide to distribute it in future.

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The existence of four of sickle-type hemoglobin suggests that this mutation has emerged at least four times in malaria-endemic areas, further demonstrating its evolutionary advantage in such affected regions.

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Otro estudio examin el mismo grupo de hombres y hall una relacin entre la obesidad clnica, es decir, un ndice de masa corporal superior a 30, y un flujo de sangre reducido al pene.

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Particularly active programmes in Latin America, South Asia, and Africa consumed a substantial proportion of national health expenditures, as well as major inputs from the World Health Organization and donor governments.

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Yet, after observing the trial over the course of the malaria season, many of the caregivers who had refused or withdrawn their children and those whose children had not been eligible to participate actively lobbied “to be included in the project.

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How much drug pressure, either in total dose or duration of exposure, is required to lead to a detectable change in the distribution of drug-resistant malaria is not known.

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Ghana compared delivery of IPTc at fixed locations in villages with a facility-based delivery strategy and concluded that “to maximise the impact of IPTc, both delivery systems may be needed in some settings.

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We report here that chloroquine is able to inhibit influenza A virus replication, in vitro, and the IC50s (and IC90) of chloroquine against influenza A viruses H1N1 and H3N2 are lower than the plasma concentrations reached during treatment of acute malaria.

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However, a genetic deficiency in this enzyme results in increased protection against severe malaria.

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The Kruger Park does fall within a malaria risk area and although the risk is low, anti-malaria medication or prophylactics are recommended for visitors to the area.

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PPCIXCC sequence also present in E3 proteins from 50% of Alphaviruses, including that from ONNV ().

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Where there is frequent or high level resistance, such as the Assam region discussed above, alternative agents are used.

It should be taken regularly thoughout the stay and continued for four weeks after leaving the malarious area.

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Interestingly, peptides that mimic the E2 tail of Alphaviruses, inhibit virus production probably by preventing C-E2 interactions ().

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The genome of the S27 CHIKV strain, similarly to the other Alphaviruses, contains two open reading frame (ORF) of 7424 nt and 3732 nt that encode non-structural and structural proteins of CHIKV, respectively ().

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T-cell and antibody responses induced by primary vaccination persisted for at least 3 years.

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Similarly, despite it was concluded from preliminary results, that no kinase activity was incorporated into Alphaviruses () low kinase activity has been found specifically associated with viral preparations of SINV and SFV ultrapurified by co-sedimentation in sucrose ().

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In expressing enthusiasm for IPTc or for “the project” in general, participants often explained the advantages in terms of the benefits of the free curative care.

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This public-health work saved the lives of thousands of workers and helped develop the methods used in future public-health campaigns against this disease.

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