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How does fludrocortisone increase blood pressure? Fludrocortisone is also used to raise blood pressure in people with postural hypotension, but it does not have a UK licence for this, and so its use to treat postural hypotension is called 'off-label'. It raises blood pressure by increasing sodium (salt) levels and affecting blood volume.
How is fludrocortisone administered? The usual dose is 0.1 mg of Florinef Acetate daily, although dosage ranging from 0.1 mg three times a week to 0.2 mg daily has been employed. Florinef Acetate is preferably administered in conjunction with cortisone (10 mg to 37.5 mg daily in divided doses) or hydrocortisone (10 mg to 30 mg daily in divided doses).
How long does fludrocortisone last? Fludrocortisone is given at 0.1 to 0.5 mg daily; however, with a half-life of 36 hours, a clinical effect typically is not seen for several days.
What is florinef used to treat? It is used along with other medications (e.g., hydrocortisone) to treat low glucocorticoid levels caused by disease of the adrenal gland (e.g., Addison's disease, adrenocortical insufficiency, salt-losing adrenogenital syndrome). Glucocorticoids are needed in many ways for the body to function well.
Is fludrocortisone a corticosteroid? Fludrocortisone, sold under the brand name Florinef among others, is a corticosteroid which is used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. Fludrocortisone is mostly a mineralocorticoid; however, also has glucocorticoid effects.
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