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Between-group differences for continuous variables for change scores during the DB phase were assessed using analysis of co-variance models.
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We hypothesized that there would be significant differences in the overall effectiveness of olanzapine, perphenazine, quetiapine, risperidone, and ziprasidone in treating schizophrenia that reflected variations in efficacy and tolerability.
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For psychosis, outcome was generally poor with only 10% achieving a 25% reduction in total PANSS scores from pretreatment to long-term follow-up, also cost-effectiveness analysis showed no advantages of CBT over non-CBT.
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However, a number of medications approved for the treatment of other mental health conditions also may be helpful for schizoaffective disorder.
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