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Which Drugs Or Supplements Interact With Desvenlafaxine (Pristiq)? These embody how long the medication was taken, individual parts, the dosage, and the way quickly the drug was faraway from the treatment plan. If you do gain some weight whereas taking an antidepressant, the drug could not truly be the direct cause of the load gain. An improved temper while taking an antidepressant, for example, may increase your urge for food, leading to weight acquire. Doctors prescribe MAOIs most often when different antidepressants don’t work because of sure unwanted side effects and safety issues. Of the three MAOIs listed above, phenelzine is the most probably to lead to weight achieve, based on a 1988 evaluation. Allow ≥14 days after MAOI discontinuance earlier than starting desvenlafaxine; allow ≥7 days after desvenlafaxine discontinuance earlier than starting an MAOI.Based on the half-lifetime of desvenlafaxine succinate, at least 7 days must be allowed after stopping desvenlafaxine succinate and earlier than starting an MAOI.Increased threat of serotonin syndrome with different serotonergic drugs (eg, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, St. John's Wort) or with medication that impair serotonin metabolism . desvenlafaxine Desvenlafaxine capsules price. Weight achieve was a typical reason individuals stopped treatment with these types of antidepressants, in accordance with a 1984 examine. A specific therapy to reverse the effects of desvenlafaxine doesn't exist. Medical consideration must be sought if serotonin syndrome is suspected. you should know that desvenlafaxine may cause angle-closure glaucoma . Drug hamlet major depressive disorder.